9RAF

Influenza A/H7N9 polymerase in complex with a 70-mer template in stalled elongation with backtracking and stem.

Summary for 9RAF

• Entry DOI: 10.2210/pdb9raf/pdb
• EMDB information: 53876
• Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA Pol II CTD 6 repeats (site 1A/2A), ... (8 entities in total)
• Functional Keywords: influenza polymerase, viral protein
• Biological source: Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)); More
• Total number of polymer chains: 6
• Total formula weight: 289833.36

Authors

Arragain, B.,Cusack, S. (deposition date: 2025-05-20, release date: 2026-03-11)

• Primary citation: Funk, M.,Spronken, M.I.,Hutchinson, R.,Arragain, B.,Juyoux, P.,Bestebroer, T.M.,de Bruin, A.C.,Gultyaev, A.P.,Fouchier, R.A.M.,Cusack, S.,te Vulthuis, A.J.W.,Richard, M.; Polymerase trapping as mechanism of H5 highly pathogenic avian influenza virus genesis; Science, 2026; DOI: 10.1126/science.adr6632

Experimental method

ELECTRON MICROSCOPY (2.15 Å)