9R8S
A viral SAVED protein with ring nuclease activity subverts type III CRISPR defence
Summary for 9R8S
Entry DOI | 10.2210/pdb9r8s/pdb |
Descriptor | SMODS-associated and fused to various effectors domain-containing protein, PHOSPHATE ION (3 entities in total) |
Functional Keywords | saved anti-crispr defense, viral protein |
Biological source | Thermocrinis Great Boiling Spring virus |
Total number of polymer chains | 2 |
Total formula weight | 55451.65 |
Authors | McMahon, S.A.,White, M.F.,Orzechowski, M.,Hoikkala, V.,Chi, H.,Gloster, T.M. (deposition date: 2025-05-16, release date: 2025-07-02) |
Primary citation | Orzechowski, M.,Hoikkala, V.,Chi, H.,McMahon, S.A.,Gloster, T.M.,White, M.F. A viral SAVED protein with ring nuclease activity degrades the CRISPR second messenger cA4 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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