9R2F

Tau filaments seeded by AD homogenate using 0N3R C322A

Summary for 9R2F

• Entry DOI: 10.2210/pdb9r2f/pdb
• EMDB information: 53527
• Descriptor: Isoform Fetal-tau of Microtubule-associated protein tau (1 entity in total)
• Functional Keywords: mapt, tau, alzheimer's disease, rt-quic, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 46853.67

Authors

Lovestam, S.,Scheres, H.W.S. (deposition date: 2025-04-30, release date: 2025-06-11)

• Primary citation: Santambrogio, A.,Lovestam, S.,Metrick, A.M.,Lohr, S.T.,Xu, P.,Caughey, B.,Scheres, H.W.S.,Vendruscolo, M.; Serial amplification of tau filaments using Alzheimers brain homogenates and C322A or C322S recombinant tau; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.8 Å)