9QRM

X-ray structure of Kp32gp38 in complex with K21 pyr5

これはPDB形式変換不可エントリーです。

9QRM の概要

• エントリーDOI: 10.2210/pdb9qrm/pdb
• 分子名称: Depolymerase 2, capsule K21-specific, (2~{S},4~{a}~{S},6~{R},7~{S},8~{R},8~{a}~{R})-2-methyl-6,7,8-tris(oxidanyl)-4,4~{a},6,7,8,8~{a}-hexahydropyrano[3,2-d][1,3]dioxine-2-carboxylic acid-(4-4)-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-galactopyranose, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: klebsiella pneumoniae, phage depolymerase, protein structure, cps degradation, immune response induction, viral protein
• 由来する生物種: Klebsiella pneumoniae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 63943.58

構造登録者

Napolitano, V.,Squeglia, F.,Privitera, M.,Berisio, R. (登録日: 2025-04-03, 公開日: 2025-09-03, 最終更新日: 2025-10-01)

主引用文献

Napolitano, V.,Privitera, M.,Drulis-Kawa, Z.,Marasco, D.,Fallarini, S.,Berisio, R.,Squeglia, F.
Structural and functional features of Klebsiella pneumoniae capsular degradation by the phage depolymerase KP32gp38: Implications for vaccination against K. pneumoniae.
Int J Antimicrob Agents, 66:107596-107596, 2025

PubMed Abstract: Klebsiella pneumoniae Przondovirus KP32 presents a complex capsular degradation machinery comprised of two serotype-specific depolymerases, KP32gp38 and KP32gp37.

PubMed: 40846037
DOI: 10.1016/j.ijantimicag.2025.107596

実験手法

X-RAY DIFFRACTION (1.8 Å)