Summary for 9QBA
Entry DOI | 10.2210/pdb9qba/pdb |
Descriptor | E3 ubiquitin-protein ligase TRIM21, ~{N}-(cyclohexylmethyl)-4-(4-fluoranyl-2-methylsulfanyl-phenyl)-2-methylsulfonyl-benzamide, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | trim21, pryspry domain, e3 ligase, inhibitor, ligase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 20892.57 |
Authors | Kim, Y.,Lucic, A.,Knapp, S.,Kraemer, A.,Structural Genomics Consortium (SGC) (deposition date: 2025-03-01, release date: 2025-03-12, Last modification date: 2025-03-26) |
Primary citation | Kim, Y.,Lucic, A.,Knapp, S.,Kraemer, A.,Structural Genomics Consortium (SGC) Human TRIM21 PRYSPRY domain in complex with AL236 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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