9Q9R

TRIM21 PRYSPRY bound to compound 209

This is a non-PDB format compatible entry.

Summary for 9Q9R

• Entry DOI: 10.2210/pdb9q9r/pdb
• Descriptor: E3 ubiquitin-protein ligase TRIM21, (2~{S},4~{S})-1-[(3~{S})-3-azanyl-3-[2-[2-(2-hydroxyethyloxy)ethoxy]phenyl]propanoyl]-4-cyclohexyl-~{N}-[(2~{S})-1-(methylamino)-1-oxidanylidene-3-pyridin-4-yl-propan-2-yl]pyrrolidine-2-carboxamide (3 entities in total)
• Functional Keywords: trim21, e3 ligase, protac, pryspry, ligase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 23127.99

Authors

Luptak, J. (deposition date: 2025-02-26, release date: 2025-10-08)

• Primary citation: Luptak, J.,James, L.C.; Development of TRIM21 PROTAC molecules; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.331 Å)