9Q7X
Crystal structure of the MKP5 loop mutant N448A in complex with the allosteric inhibitor
Summary for 9Q7X
| Entry DOI | 10.2210/pdb9q7x/pdb |
| Descriptor | Dual specificity protein phosphatase 10, 3,3-dimethyl-1-{[9-(methylsulfanyl)-5,6-dihydrothieno[3,4-h]quinazolin-2-yl]sulfanyl}butan-2-one (2 entities in total) |
| Functional Keywords | mkp5, allosteric inhibitor, allosteric site, hydrolase-inhibitor complex, hydrolase/inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 6 |
| Total formula weight | 104328.65 |
| Authors | |
| Primary citation | Manjula, R.,Bennett, A.M.,Lolis, E. Crystal structure of the MKP5 loop mutant N448A in complex with the allosteric inhibitor To Be Published, |
| Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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