9PY2

Engaged-state loperamide-mu opioid receptor-Gi GDPbS complex (rebound)

This is a non-PDB format compatible entry.

Summary for 9PY2

• Entry DOI: 10.2210/pdb9py2/pdb
• EMDB information: 72006
• Descriptor: Soluble cytochrome b562,Mu-type opioid receptor, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total)
• Functional Keywords: g protein coupled receptor, mu opioid receptor, loperamide, membrane protein, gdp
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 159365.62

Authors

Gati, C.,Han, G.W.,Khan, S. (deposition date: 2025-08-06, release date: 2025-11-12)

• Primary citation: Khan, S.,Tyson, A.S.,Ranjbar, M.,Zhang, Z.,Singh, J.,Han, G.W.,Gati, C.; Structural snapshots capture nucleotide release at the mu-opioid receptor; Nature, 2025; DOI: 10.1038/s41586-025-09677-6

Experimental method

ELECTRON MICROSCOPY (3.16 Å)