9PLM

TRIM21-NUP98 Molecular Glue Complex (MAN-021)

This is a non-PDB format compatible entry.

Summary for 9PLM

• Entry DOI: 10.2210/pdb9plm/pdb
• Related: 9PLL
• Descriptor: E3 ubiquitin-protein ligase TRIM21, Isoform 2 of Nuclear pore complex protein Nup98-Nup96, (3P)-3-{4-chloro-2-[2-(dimethylamino)ethoxy]phenyl}-6-fluoro-2-[(piperazin-1-yl)methyl]quinazolin-4(3H)-one, ... (5 entities in total)
• Functional Keywords: molecular glue, ubiquitin ligase, trim21, targeted protein degradation, ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 41283.81

Authors

Hinshaw, S.M.,Martinez, M.,Fernandez, D.,Gray, N.S.,Yuan, L.,Noman, M.A.,Corsello, S.M. (deposition date: 2025-07-15, release date: 2026-05-27)

• Primary citation: Hinshaw, S.M.,Martinez, M.,Fernandez, D.,Gray, N.S.,Yuan, L.,Noman, M.A.,Corsello, S.M.; TRIM21-NUP98 Molecular Glue Complex (MAN-021); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.32 Å)