9PFP

Structure of POU2F3 POU domains bound to coactivator OCA-T1 and DNA

Summary for 9PFP

• Entry DOI: 10.2210/pdb9pfp/pdb
• Related: 1CQT 1OCT 9PFN 9PFO
• Descriptor: POU domain, class 2, transcription factor 3, POU domain class 2-associating factor 2, DNA containing POU domain recognition element octamer (sense strand), ... (6 entities in total)
• Functional Keywords: transcription factor, dna binding, coactivator complex, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 64553.80

Authors

Ipsaro, J.J.,Alpsoy, A.,Vakoc, C.R.,Joshua-Tor, L. (deposition date: 2025-07-06, release date: 2025-10-01)

• Primary citation: Alpsoy, A.,Ipsaro, J.J.,Skopelitis, D.,Pal, S.,Chung, F.S.,Carpenter, S.,Desmarais, J.,Wu, X.S.,Chang, K.,DiMare, M.T.,Harten, E.,Bergman, S.,Kinney, J.,Engelman, J.A.,Bhang, H.C.,Joshua-Tor, L.,Vakoc, C.R.; Structural Basis of DNA-Dependent Coactivator Recruitment by the Tuft Cell Master Regulator POU2F3; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)