9OUK

DDB1-CRBN with Ikaros(ZF2) and DEG-47: composite map and model submission

This is a non-PDB format compatible entry.

Summary for 9OUK

• Entry DOI: 10.2210/pdb9ouk/pdb
• EMDB information: 70867
• Descriptor: DNA damage-binding protein 1, Protein cereblon, DNA-binding protein Ikaros, ... (5 entities in total)
• Functional Keywords: e3 ligases, cullin ring ligase, crl4, cereblon, crbn, molecular glues, imids, ligase, ikaros
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 152986.70

Authors

Rizvi, Z.,Lander, G.C. (deposition date: 2025-05-28, release date: 2025-12-03)

• Primary citation: Rizvi, Z.,Dippon, V.N.,Choudhry, A.E.,Chung, C.W.,Alkuraya, I.F.,Xu, W.,Tao, X.B.,Jurewicz, A.J.,Schneck, J.L.,Chen, W.,Curnutt, N.M.,Kabir, F.,Chan, K.H.,Queisser, M.A.,Musetti, C.,Dai, H.,Benowitz, A.B.,Woo, C.M.,Lander, G.C.; Identification of a cryptic allosteric site on the E3 ligase adapter protein cereblon; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.69 Å)