9OIM

The von Hippel Lindau-ElonginB-ElonginC (VCB) complex with fragment 9

This is a non-PDB format compatible entry.

Summary for 9OIM

• Entry DOI: 10.2210/pdb9oim/pdb
• Descriptor: Elongin-B, Elongin-C, von Hippel-Lindau disease tumor suppressor, ... (6 entities in total)
• Functional Keywords: vhl, e3 ligase, fragment-based drug discovery, protein transport
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 175799.06

Authors

Amporndanai, K.,Katinas, J.M.,Chopra, A.,Fesik, S.W. (deposition date: 2025-05-06, release date: 2025-07-09)

• Primary citation: Amporndanai, K.,Katinas, J.M.,Chopra, A.,Kayode, O.,Vadukoot, A.K.,Waterson, A.G.,Fesik, S.W.; NMR-Based Fragment Screen of the von Hippel-Lindau Elongin C&B Complex; Acs Med.Chem.Lett., 2025; DOI: 10.1021/acsmedchemlett.5c00316

Experimental method

X-RAY DIFFRACTION (2.61 Å)