9OFC

CryoEM structure of Cad1 bound with cA4 and ATP, hexamer with three intact dimers

Summary for 9OFC

• Entry DOI: 10.2210/pdb9ofc/pdb
• Related: 9EBT 9EKA 9OF1
• EMDB information: 70428
• Descriptor: CRISPR-associated ring nuclease and adenosine deaminase, subunit A, cA4 cleavage product, A2>P, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: crispr-associated rossman-fold (carf), atp deaminase, crispr immunity, cooperative activation, immune system, hydrolase
• Biological source: Thermoanaerobaculum aquaticum; More
• Total number of polymer chains: 12
• Total formula weight: 424677.29

Authors

Zhao, Y.,Li, H. (deposition date: 2025-04-29, release date: 2025-08-20)

• Primary citation: Roth, M.,Shu, Y.,Trasandidou, D.,Zhao, Y.,van der Oost, J.,Li, H.; Sequential Conformational Activation of a CARF-Fused Adenosine Deaminase by Cyclic Oligoadenylates; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.17 Å)