9O4L

Crystal structure of Human p38 alpha MAPK in Complex with MW01-8 -066WH

This is a non-PDB format compatible entry.

Summary for 9O4L

• Entry DOI: 10.2210/pdb9o4l/pdb
• Descriptor: Mitogen-activated protein kinase 14, 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE, 6-(4-methylpiperazin-1-yl)-3-phenyl-4-(pyridin-4-yl)pyridazine, ... (4 entities in total)
• Functional Keywords: serine/threonine-protein kinase, protein kinase domain, transferase, atp binding, phosphorylation, cytosol, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 44657.76

Authors

Brunzelle, J.S.,Shuvalova, L.,Roy, S.M.,Watterson, D.M. (deposition date: 2025-04-08, release date: 2025-04-30)

• Primary citation: Brunzelle, J.S.,Shuvalova, L.,Roy, S.M.,Watterson, D.M.; Crystal structure of Human p38 alpha MAPK in Complex with MW01-8 -066WH; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.27 Å)