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9NQZ

cryo-EM structure of broad betacoronavirus binding antibody 1871 in complex with OC43 S2 subunit

Summary for 9NQZ
Entry DOI10.2210/pdb9nqz/pdb
EMDB information49708
DescriptorSpike glycoprotein, 1871 Fab light chain, 1871 Fab heavy chain (3 entities in total)
Functional Keywordsoc43, betacoronavirus, antibody, viral glycoprotein, immune system-viral protein complex, viral protein, viral protein-immune system complex, viral protein/immune system
Biological sourceHuman coronavirus OC43
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Total number of polymer chains9
Total formula weight269365.95
Authors
Muthuraman, K.,Jackman, M.J.,Julien, J.P. (deposition date: 2025-03-13, release date: 2025-11-12)
Primary citationMuthuraman, K.,Jackman, M.J.,Julien, J.P.
Human antibody targeting of coronavirus spike S2 subunit is associated with protection mediated by Fc effector functions
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.6 Å)
Structure validation

245011

数据于2025-11-19公开中

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