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9MX1

Clostridioides difficile Toxin A with mCDIFA-248-25 Fab

Summary for 9MX1
Entry DOI10.2210/pdb9mx1/pdb
EMDB information48707
DescriptorToxin A, mCDIFA-248-25 Fab Heavy Chain, mCDIFA-248-25 Fab Light Chain (3 entities in total)
Functional Keywordstoxin a, tcda, c.diff, complex, transferase, toxin-immune system complex, toxin/immune system
Biological sourceClostridioides difficile
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Total number of polymer chains3
Total formula weight355712.00
Authors
Huynh, K.W.,Ammirati, M.,Kroh, H.K.,Lacy, D.B.,Han, S. (deposition date: 2025-01-17, release date: 2025-07-09)
Primary citationKroh, H.K.,Jensen, J.L.,Wellnitz, S.,Park, J.J.,Esadze, A.,Huynh, K.W.,Ammirati, M.,Han, S.,Anderson, A.S.,Lacy, D.B.,Gribenko, A.
Mouse monoclonal antibodies against Clostridioides difficile toxins TcdA and TcdB target diverse epitopes for neutralization
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.2 Å)
Structure validation

240971

数据于2025-08-27公开中

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