9MV0

Structure of HKU5 spike C-terminal domain in complex with ACE2 from Pipistrellus abramus

Summary for 9MV0

• Entry DOI: 10.2210/pdb9mv0/pdb
• EMDB information: 48650
• Descriptor: Angiotensin-converting enzyme, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: immune system, ace2, bat coronavirus, merbecovirus, hku5, viral protein
• Biological source: Pipistrellus abramus; More
• Total number of polymer chains: 4
• Total formula weight: 488843.47

Authors

Li, N.,Tsybovsky, Y.,Teng, I.,Zhou, T. (deposition date: 2025-01-15, release date: 2025-07-30)

• Primary citation: Madel Alfajaro, M.,Keeler, E.L.,Li, N.,Catanzaro, N.J.,Teng, I.T.,Zhao, Z.,Grunst, M.W.,Yount, B.,Schafer, A.,Wang, D.,Kim, A.S.,Synowiec, A.,Pena-Hernandez, M.A.,Zepeda, S.,Arinola, R.,Kaur, R.,Menasche, B.L.,Wei, J.,Russell, G.A.,Huck, J.,Song, J.,Ring, A.,Iwasaki, A.,Jangra, R.K.,Lee, S.,Martinez, D.R.,Mothes, W.,Uchil, P.D.,Doench, J.G.,Spaulding, A.B.,Baric, R.S.,Serebryannyy, L.,Tsybovsky, Y.,Zhou, T.,Douek, D.C.,Wilen, C.B.; HKU5 bat merbecoviruses engage bat and mink ACE2 as entry receptors; Nat Commun, 16:6822-, 2025; DOI: 10.1038/s41467-025-61583-7

Experimental method

ELECTRON MICROSCOPY (4.2 Å)