9MKN

Structure of the Respiratory Syncytial Virus Fusion Protein Bound to Human Antibodies RSV_2245 and RSV_3301

Summary for 9MKN

• Entry DOI: 10.2210/pdb9mkn/pdb
• EMDB information: 48331
• Descriptor: Fusion glycoprotein F2, Fusion glycoprotein F1, 2245 Fab Heavy Chain, ... (6 entities in total)
• Functional Keywords: fusion protein, trimer, antibody, complex, antiviral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Respiratory syncytial virus; More
• Total number of polymer chains: 18
• Total formula weight: 434849.69

Authors

Johnson, N.V.,McLellan, J.S. (deposition date: 2024-12-17, release date: 2025-10-29)

• Primary citation: Wasdin, P.T.,Johnson, N.V.,Janke, A.K.,Held, S.,Marinov, T.M.,Jordaan, G.,Vandenabeele, L.,Pantouli, F.,Gillespie, R.A.,Vukovich, M.J.,Holt, C.M.,Kim, J.R.,Hansman, G.,Logue, J.,Chu, H.Y.,Andrews, S.F.,Kanekiyo, M.,Sautto, G.,Ross, T.,Sheward, D.J.,McLellan, J.S.,Abu-Shmais, A.A.,Georgiev, I.S.; Generation of antigen-specific paired heavy-light chain antibody sequences using large language models; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.4 Å)