9MG4

Structure of Saccharomyces cerevisiae mRNA cap (guanine-N7) methyltransferase, Abd1, in complex with SAH

Summary for 9MG4

• Entry DOI: 10.2210/pdb9mg4/pdb
• Related: 9MG5 9MG6
• Descriptor: mRNA cap guanine-N7 methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: methyltransferase, mrna, cap, sah, transferase, abd1, s. cerevisiae
• Biological source: Saccharomyces cerevisiae YJM789
• Total number of polymer chains: 1
• Total formula weight: 34931.57

Authors

Nilson, D.J.,Fedorov, E.,Ghosh, A. (deposition date: 2024-12-10, release date: 2025-07-09)

• Primary citation: Nilson, D.J.,Schwer, B.,Shuman, S.,Almo, S.C.; Structural basis for sensitivity and acquired resistance of fungal cap guanine-N7 methyltransferases to the antifungal antibiotic Sinefungin; Nucleic Acids Res., 2025; DOI: 10.1093/nar/gkaf538

Experimental method

X-RAY DIFFRACTION (1.75 Å)