9KMC

Cryo-EM structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2 and anti-CD25 Fab S417

Summary for 9KMC

• Entry DOI: 10.2210/pdb9kmc/pdb
• EMDB information: 62427
• Descriptor: Interleukin-2 receptor subunit alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-2 receptor subunit beta, ... (10 entities in total)
• Functional Keywords: cytokine, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 146775.96

Authors

Katsura, K.,Matsumoto, T.,Shirouzu, M. (deposition date: 2024-11-15, release date: 2025-11-19)

• Primary citation: Itoh-Nakadai, A.,Liang, M.,Ishikawa, F.; CXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.97 Å)