9K1K

Yeast Cytosine Deaminase mutant-M100H

Summary for 9K1K

• Entry DOI: 10.2210/pdb9k1k/pdb
• Descriptor: Cytosine deaminase, ZINC ION (3 entities in total)
• Functional Keywords: cytosine deaminase, antitumor protein
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
• Total number of polymer chains: 2
• Total formula weight: 35335.57

Authors

Yung, K.W.Y.,Zheng, J.L.,Chan, M.K. (deposition date: 2024-10-16, release date: 2025-10-22)

• Primary citation: Zheng, J.L.,Zhou, J.H.,Yung, K.W.Y.,Lee, M.M.,Chan, M.K.; An engineered yeast cytosine deaminase with improved catalytic activity and stability for macrophage-mediated enzyme/prodrug therapy; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.439 Å)