9K07

Cryo-EM structure of the DSO-5a-bound human BRS3-Gq complex

This is a non-PDB format compatible entry.

Summary for 9K07

• Entry DOI: 10.2210/pdb9k07/pdb
• EMDB information: 61941
• Descriptor: Bombesin receptor subtype-3,Oplophorus-luciferin 2-monooxygenase catalytic subunit, Guanine nucleotide-binding protein G(i) subunit alpha-2,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, scFv16, ... (7 entities in total)
• Functional Keywords: dso-5a, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 185640.22

Authors

Li, J.,Li, C.,Zhou, Q.,Han, W.,Fang, M.,Xu, Y.,Mai, Y.,Cui, J.,Xu, H.,Zhang, Y.,Yin, W.,Wang, M. (deposition date: 2024-10-15, release date: 2025-08-27)

• Primary citation: Li, J.,Li, C.,Zhou, Q.,Han, W.,Fang, M.,Xu, Y.,Mai, Y.,Zhang, Y.,Cui, J.,Xu, H.E.,Zhang, Y.,Yin, W.,Wang, M.W.; Divergent activation patterns of BRS3 revealed by two Chinese herb-derived agonists; Acta Pharm Sin B, 2025; DOI: 10.1016/j.apsb.2025.06.025

Experimental method

ELECTRON MICROSCOPY (2.83 Å)