9JMX

Crystal structure of IRED-M235A in complex with NADP+ and substrate

This is a non-PDB format compatible entry.

Summary for 9JMX

• Entry DOI: 10.2210/pdb9jmx/pdb
• Descriptor: 3-hydroxyisobutyrate dehydrogenase-like beta-hydroxyacid dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 1-~{tert}-butyl-4,9-dihydro-3~{H}-pyrido[3,4-b]indole, ... (4 entities in total)
• Functional Keywords: imine reductase, oxidoreductase
• Biological source: Amycolatopsis thermoflava
• Total number of polymer chains: 2
• Total formula weight: 62211.71

Authors

Fu, X.L.,Zhang, M.T.,Yi, S.M.,Dai, K.X.,Yang, Y.Y.,Chen, C.-C.,Guo, R.-T. (deposition date: 2024-09-21, release date: 2025-07-23, Last modification date: 2025-09-03)

• Primary citation: Li, Y.,Yang, Y.,Zhang, M.,Yue, X.,Guo, R.T.,Huang, Z.,Chen, F.; Mutagenesis of a Single Site Inverts the Stereopreference of Imine Reductase; Acs Catalysis, 15:2192-2199, 2025; DOI: 10.1021/acscatal.5c00046

Experimental method

X-RAY DIFFRACTION (2.04 Å)