9JD5

Cryo-EM structure of human TauT in presence of Taurocyamine, determined in an inward-facing occluded conformation

9JD5 の概要

• エントリーDOI: 10.2210/pdb9jd5/pdb
• EMDBエントリー: 61381
• 分子名称: Sodium- and chloride-dependent taurine transporter, 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... (7 entities in total)
• 機能のキーワード: human taurine transporter, taurocyamine, complex, inward-facing occluded conformation, transport protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 70868.41

構造登録者

Qu, Q.,Chao, Y.,Zhou, Z. (登録日: 2024-08-30, 公開日: 2025-03-19, 最終更新日: 2025-05-07)

• 主引用文献: Chao, Y.,Zhou, Z.,Xia, H.,Yang, C.,Li, T.,Tang, Y.Q.,Shu, Y.,Ba, Q.,Hong, J.,Li, D.,Qu, Q.; Transport and inhibition mechanism for human TauT-mediated taurine uptake.; Cell Res., 35:381-384, 2025; PubMed: 39837997; DOI: 10.1038/s41422-025-01076-w

実験手法

ELECTRON MICROSCOPY (2.58 Å)