9JBQ

Structure of the complex between h1F3 Fab and PcrV fragment

Summary for 9JBQ

• Entry DOI: 10.2210/pdb9jbq/pdb
• Descriptor: Heavy chain, light chain, PcrV, ... (4 entities in total)
• Functional Keywords: complex, fab, antimicrobial protein, antimicrobial protein-immune system complex, antimicrobial protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 62646.86

Authors

Numata, S.,Hara, T.,Izawa, M.,Okuno, Y.,Sato, Y.,Yamane, S.,Maki, H.,Sato, T.,Yamano, Y. (deposition date: 2024-08-27, release date: 2024-09-11, Last modification date: 2024-10-16)

• Primary citation: Numata, S.,Hara, T.,Izawa, M.,Okuno, Y.,Sato, Y.,Yamane, S.,Maki, H.,Sato, T.,Yamano, Y.; Novel humanized anti-PcrV monoclonal antibody COT-143 protects mice from lethal Pseudomonas aeruginosa infection via inhibition of toxin translocation by the type III secretion system.; Antimicrob.Agents Chemother., 68:e0069424-e0069424, 2024; PubMed: 39269189; DOI: 10.1128/aac.00694-24

Experimental method

X-RAY DIFFRACTION (2 Å)