9IBY

Crystal structure of Zika Virus NS2B-NS3 protease in complex with compound 2

This is a non-PDB format compatible entry.

Summary for 9IBY

• Entry DOI: 10.2210/pdb9iby/pdb
• Descriptor: Genome polyprotein, 1-[3-[[5-(4,6-dimethylpyrimidin-5-yl)pyridin-2-yl]methyl]-1-oxa-2,3$l^{4}-diazacyclopenta-2,4-dien-5-yl]-3-[3-(trifluoromethyl)phenyl]urea, ACETIC ACID, ... (4 entities in total)
• Functional Keywords: zika virus, ns2b-ns3 protease, allosteric inhibitor, compound 1, hydrolase
• Biological source: Zika virus; More
• Total number of polymer chains: 2
• Total formula weight: 49827.19

Authors

Ontario, J.M.,Torrente, E. (deposition date: 2025-02-14, release date: 2025-12-03)

• Primary citation: Ontoria, J.M.,Torrente, E.; Crystal structure of Zika Virus NS2B-NS3 protease in complex with compounds to be submitted; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.291 Å)