9HPB
Mouse phosphomannomutase 2 in apo state from crystals with PEG 8000
Summary for 9HPB
| Entry DOI | 10.2210/pdb9hpb/pdb |
| Descriptor | Phosphomannomutase 2, MAGNESIUM ION, CHLORIDE ION, ... (5 entities in total) |
| Functional Keywords | n-glycosylation, congenital disorder of glycosylation, carbohydrate-deficient, hypoglycosylation, homodimer, phosphoglucomutase, nucleotide-sugar biosynthesis, mannose-1-phosphate, gdp-mannose, isomeras, isomerase |
| Biological source | Mus musculus (house mouse) |
| Total number of polymer chains | 6 |
| Total formula weight | 167594.01 |
| Authors | Ramon-Maiques, S.,Del Cano-Ochoa, F.,Company, R. (deposition date: 2024-12-12, release date: 2025-12-24) |
| Primary citation | Del Cano-Ochoa, F.,Vilar, M.,Vilas, A.,Company, R.,Perez, B.,Ramon-Maiques, S. High conformational flexibility of phosphomannomutase 2: Implications for functioning mechanisms, stability and pharmacological chaperone design To Be Published, |
| Experimental method | X-RAY DIFFRACTION (2.43 Å) |
Structure validation
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