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9HPB

Mouse phosphomannomutase 2 in apo state from crystals with PEG 8000

Summary for 9HPB
Entry DOI10.2210/pdb9hpb/pdb
DescriptorPhosphomannomutase 2, MAGNESIUM ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsn-glycosylation, congenital disorder of glycosylation, carbohydrate-deficient, hypoglycosylation, homodimer, phosphoglucomutase, nucleotide-sugar biosynthesis, mannose-1-phosphate, gdp-mannose, isomeras, isomerase
Biological sourceMus musculus (house mouse)
Total number of polymer chains6
Total formula weight167594.01
Authors
Ramon-Maiques, S.,Del Cano-Ochoa, F.,Company, R. (deposition date: 2024-12-12, release date: 2025-12-24)
Primary citationDel Cano-Ochoa, F.,Vilar, M.,Vilas, A.,Company, R.,Perez, B.,Ramon-Maiques, S.
High conformational flexibility of phosphomannomutase 2: Implications for functioning mechanisms, stability and pharmacological chaperone design
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.43 Å)
Structure validation

248942

건을2026-02-11부터공개중

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