9GQP

Structural characterization of a N-acetyl-beta-neuraminic acid-binding site in human RNase2

9GQP の概要

• エントリーDOI: 10.2210/pdb9gqp/pdb
• 分子名称: Non-secretory ribonuclease, N-acetyl-beta-neuraminic acid, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
• 機能のキーワード: monosaccharide, sialic acid, rnase, immune system, protein binding
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17190.21

構造登録者

Xincheng, K.,Jiarui, L.,Prats-Ejarque, G.,Boix, E. (登録日: 2024-09-09, 公開日: 2026-03-18, 最終更新日: 2026-04-22)

• 主引用文献: Kang, X.,Prats-Ejarque, G.,Boix, E.,Li, J.; Structural basis for saccharide binding by human RNase 2/EDN, a protein combining enzymatic and lectin properties; Biorxiv, 2026; DOI: 10.64898/2026.03.20.713198

実験手法

X-RAY DIFFRACTION (1.01 Å)