9GEM

Crystal structure of human NUDT14 in complex with MA-12

This is a non-PDB format compatible entry.

Summary for 9GEM

• Entry DOI: 10.2210/pdb9gem/pdb
• Descriptor: Uridine diphosphate glucose pyrophosphatase NUDT14, 1-(1-methylpiperidin-4-yl)-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]pyrazolo[3,4-d]pyrimidin-4-amine (3 entities in total)
• Functional Keywords: nudix hydrolase domain, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 97706.30

Authors

Koekemoer, L.,Dlamini, L.S.,Gurav, N.,Apostolidou, M.,Adcock, C.,McGown, A.,Spencer, J.,Huber, K.V.M. (deposition date: 2024-08-07, release date: 2026-02-18, Last modification date: 2026-05-13)

• Primary citation: Koekemoer, L.,Gurav, N.,Apostolidou, M.,Adcock, C.,McGown, A.,Spencer, J.,Huber, K.V.M.; Crystal structure of human NUDT14 in complex with MA-12; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.015 Å)