9FXP
Crystal structure of BRD4 BD1 with DI00626383.
Summary for 9FXP
Entry DOI | 10.2210/pdb9fxp/pdb |
Descriptor | Bromodomain-containing protein 4, 4-methoxy-1,2-benzoxazol-3-amine (3 entities in total) |
Functional Keywords | inhibitor, bromodomain, protein binding |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 15263.54 |
Authors | Bader, G.,Reinert, D. (deposition date: 2024-07-02, release date: 2024-08-07, Last modification date: 2024-08-21) |
Primary citation | Beier, A.,Platzer, G.,Hofurthner, T.,Ptaszek, A.L.,Lichtenecker, R.J.,Geist, L.,Fuchs, J.E.,McConnell, D.B.,Mayer, M.,Konrat, R. Probing Protein-Ligand Methyl-pi Interaction Geometries through Chemical Shift Measurements of Selectively Labeled Methyl Groups. J.Med.Chem., 67:13187-13196, 2024 Cited by PubMed: 39069741DOI: 10.1021/acs.jmedchem.4c01128 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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