9FVO

The HIV protease inhibitor amprenavir binding to the active site of Cryphonectria parasitica endothiapepsin

9FVO の概要

• エントリーDOI: 10.2210/pdb9fvo/pdb
• 分子名称: Endothiapepsin, {3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER, TETRAETHYLENE GLYCOL, ... (7 entities in total)
• 機能のキーワード: aspartic protease, drug development, inhibitor, x-ray crystallographic screening, chestnut blight fungus, protease model., hydrolase
• 由来する生物種: Cryphonectria parasitica (chestnut blight fungus)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35508.81

構造登録者

Falke, S.,Senst, J.M.,Guenther, S.,Meents, A. (登録日: 2024-06-27, 公開日: 2024-07-10)

• 主引用文献: Falke, S.,Senst, J.M.,Guenther, S.,Meents, A.; The HIV protease inhibitor amprenavir binding to the active site of Cryphonectria parasitica endothiapepsin; To Be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)