9FM2

Cryo-EM structure of Influenza B/Washington/02/2019 virus neuraminidase in complex with single-domain antibody hVHH-525.

Summary for 9FM2

• Entry DOI: 10.2210/pdb9fm2/pdb
• Related: 9FM1
• EMDB information: 50546 50547
• Descriptor: Single-domain antibody hVHH-525, Neuraminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: neuraminidase, single-domain antibody, complex, antiviral protein
• Biological source: Lama glama; More
• Total number of polymer chains: 5
• Total formula weight: 228143.18

Authors

Felix, J.,Matthys, A.,Savvides, S.N.,Saelens, X. (deposition date: 2024-06-05, release date: 2025-07-09)

• Primary citation: Matthys, A.,Felix, J.,Catani, J.P.P.,Roose, K.,Nerinckx, W.,Van Buyten, B.,Fijalkowska, D.,Callewaert, N.,Savvides, S.N.,Saelens, X.; Single-domain antibodies directed against hemagglutinin and neuraminidase protect against influenza B viruses; Nat Commun, 16:5831-, 2025; DOI: 10.1038/s41467-025-60232-3

Experimental method

ELECTRON MICROSCOPY (3.6 Å)