9FM0

Human antibody (Fab) and P. aeruginosa (T3SS) protein PcrV-fragment complex

9FM0 の概要

• エントリーDOI: 10.2210/pdb9fm0/pdb
• 分子名称: Human Fab Heavy Chain (FabHC) V-region, Human Fab Light Chain (FabLC) V-region, Type III secretion protein PcrV, ... (6 entities in total)
• 機能のキーワード: human antibodies, type iii secretion system, pcrv, virulence, pseudomonas, bacterial infection, antimicrobials, anti-virulence, mab, amr, immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 123635.24

構造登録者

Desveaux, J.M.,Contreras Martel, C.,Dessen, A. (登録日: 2024-06-05, 公開日: 2025-06-18, 最終更新日: 2025-12-31)

• 主引用文献: Desveaux, J.M.,Faudry, E.,Contreras-Martel, C.,Cretin, F.,Dergan-Dylon, L.S.,Amen, A.,Bally, I.,TardivyCasemajor, V.,Chenavier, F.,Fouquenet, D.,Caspar, Y.,Attree, I.,Dessen, A.,Poignard, P.; Neutralizing human monoclonal antibodies that target the PcrV component of the Type III Secretion System of Pseudomonas aeruginosa act through distinct mechanisms; Elife, 2025; DOI: 10.7554/elife.105195.2

実験手法

X-RAY DIFFRACTION (2.56 Å)