9FGC

Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in SMALPs bound to one PIP2 molecule at chain alpha1-D and in complex with Mb38

9FGC の概要

• エントリーDOI: 10.2210/pdb9fgc/pdb
• EMDBエントリー: 50394
• 分子名称: Gamma-aminobutyric acid receptor subunit alpha-1, 2-acetamido-2-deoxy-beta-D-glucopyranose, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ... (11 entities in total)
• 機能のキーワード: gaba, neurotransmission, gating cycle, time-resolved cryo-em, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 336165.85

構造登録者

Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R. (登録日: 2024-05-23, 公開日: 2025-06-04)

• 主引用文献: Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R.; Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in SMALPs bound to one PIP2 molecule at chain alpha1-D and in complex with Mb38; To Be Published,

実験手法

ELECTRON MICROSCOPY (3.4 Å)