9FEY

Cryo-EM structure of the beta3 homomeric GABA(A) receptor in complex with HSM in the short-lived symmetric bound-closed state (C1)

Summary for 9FEY

• Entry DOI: 10.2210/pdb9fey/pdb
• EMDB information: 50345
• Descriptor: Gamma-aminobutyric acid receptor subunit beta-3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: gaba, neurotransmission, gating cycle, time-resolved cryo-em, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 236731.38

Authors

Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R. (deposition date: 2024-05-21, release date: 2025-06-04, Last modification date: 2025-08-06)

• Primary citation: Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R.; Cryo-EM structure of the beta3 homomeric GABA(A) receptor in complex with HSM in the short-lived symmetric pre-active state (C1); To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.9 Å)