9FEB

Short-chain dehydrogenase/reductase (SDR) from Thermus caliditerrae in complex with NADP

Summary for 9FEB

Entry DOI	10.2210/pdb9feb/pdb
Descriptor	SDR family oxidoreductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	short chain dehydrogenase, ketoreductase, biocatalysis, oxidoreductase
Biological source	Thermus caliditerrae
Total number of polymer chains	5
Total formula weight	153956.08
Authors	Kapur, B.,Nar, H. (deposition date: 2024-05-17, release date: 2024-06-26)
Primary citation	Sosa, Y.,Kapur, B.,Hurtak, J.,Kingsley, L.,Wu, H.,Gruber, S.,Nar, H.,Khattabi, S.,Moral, J.,Lucas, M.,Martin, C.,Loncar, N.,Buono, F.,Pefaur, N.,Nixon, A.E.,Song, J. In silico enzyme screening identifies an SDR ketoreductase from Thermus caliditerrae as an attractive biocatalyst and promising candidate for protein engineering Front Chem Biol, 2024
Experimental method	X-RAY DIFFRACTION (1.698 Å)

Structure validation