9FD3
CysG(N-16)-D190N mutant in complex with SAH from Kitasatospora cystarginea
Summary for 9FD3
Entry DOI | 10.2210/pdb9fd3/pdb |
Related | 9FCD |
Descriptor | SAM-dependent methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | natural product biosynthesis, enzyme mechanism, metal ion interaction, molecular docking, structure function relationships, transferase |
Biological source | Kitasatospora cystarginea |
Total number of polymer chains | 1 |
Total formula weight | 24848.97 |
Authors | Kuttenlochner, W.,Beller, P.,Kaysser, L.,Groll, M. (deposition date: 2024-05-16, release date: 2024-08-21, Last modification date: 2024-09-18) |
Primary citation | Kuttenlochner, W.,Beller, P.,Kaysser, L.,Groll, M. Deciphering the SAM- and metal-dependent mechanism of O-methyltransferases in cystargolide and belactosin biosynthesis: A structure-activity relationship study. J.Biol.Chem., 300:107646-107646, 2024 Cited by PubMed: 39121999DOI: 10.1016/j.jbc.2024.107646 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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