9FAP

CryoEM structure of human full-length alpha1beta3gamma2 GABA(A)R in complex with GARLH4, the TMD of Neuroligin2 and Megabody38 in a closed state (StateC1)

9FAP の概要

• エントリーDOI: 10.2210/pdb9fap/pdb
• EMDBエントリー: 50277
• 分子名称: Gamma-aminobutyric acid receptor subunit alpha-1, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ... (20 entities in total)
• 機能のキーワード: gaba, neurotransmission, ternary complex, inhibitory postsynapse, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 338438.64

構造登録者

Kasaragod, V.B.,Aricescu, A.R. (登録日: 2024-05-10, 公開日: 2025-07-02)

• 主引用文献: Kasaragod, V.B.,Aricescu, A.R.; CryoEM structure of human full-length alpha1beta3gamma2 GABA(A)R in complex with GARLH4, the TMD of Neuroligin2 and Megabody38 in a closed state (StateC1); To Be Published,

実験手法

ELECTRON MICROSCOPY (2.8 Å)