9FAA
Cryo-EM structure of cardiac collagen-associated amyloid AL59
Summary for 9FAA
| Entry DOI | 10.2210/pdb9faa/pdb |
| EMDB information | 50270 |
| Descriptor | Monoclonal immunoglobulin light chains (LC), 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total) |
| Functional Keywords | systemic al amyloid fibril, protein fibril |
| Biological source | Homo sapiens |
| Total number of polymer chains | 5 |
| Total formula weight | 70722.71 |
| Authors | Schulte, T.,Speranzini, V.,Chaves-Sanjuan, A.,Milazzo, M.,Ricagno, S. (deposition date: 2024-05-10, release date: 2024-07-17, Last modification date: 2024-08-14) |
| Primary citation | Schulte, T.,Chaves-Sanjuan, A.,Speranzini, V.,Sicking, K.,Milazzo, M.,Mazzini, G.,Rognoni, P.,Caminito, S.,Milani, P.,Marabelli, C.,Corbelli, A.,Diomede, L.,Fiordaliso, F.,Anastasia, L.,Pappone, C.,Merlini, G.,Bolognesi, M.,Nuvolone, M.,Fernandez-Busnadiego, R.,Palladini, G.,Ricagno, S. Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis. Nat Commun, 15:6359-6359, 2024 Cited by PubMed: 39069558DOI: 10.1038/s41467-024-50686-2 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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