9F9Q

Human apo pseudouridine synthase 3 (PUS3 D118A mutant)

Summary for 9F9Q

• Entry DOI: 10.2210/pdb9f9q/pdb
• EMDB information: 16917
• Descriptor: tRNA pseudouridine(38/39) synthase (1 entity in total)
• Functional Keywords: rna modification, pseudouridylation, trna, homodimer, rna binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 111408.40

Authors

Lin, T.-Y.,Glatt, S. (deposition date: 2024-05-08, release date: 2024-07-10, Last modification date: 2024-07-24)

• Primary citation: Lin, T.Y.,Kleemann, L.,Jezowski, J.,Dobosz, D.,Rawski, M.,Indyka, P.,Wazny, G.,Mehta, R.,Chramiec-Glabik, A.,Koziej, L.,Ranff, T.,Fufezan, C.,Wawro, M.,Kochan, J.,Bereta, J.,Leidel, S.A.,Glatt, S.; The molecular basis of tRNA selectivity by human pseudouridine synthase 3.; Mol.Cell, 84:2472-2489.e8, 2024; PubMed: 38996458; DOI: 10.1016/j.molcel.2024.06.013

Experimental method

ELECTRON MICROSCOPY (6.5 Å)