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9F90

Crystal structure of a designed three-motif Respiratory Syncytial Virus immunogen in complex with motavizumab fab

Summary for 9F90
Entry DOI10.2210/pdb9f90/pdb
DescriptorMotavizumab Fab light chain, Motavizumab Fab heavy chain, RSVF-multi-epitope designed scaffold, ... (5 entities in total)
Functional Keywordsdesigned immunogen, specific binding, rsv f protein, de novo protein
Biological sourceMus musculus
More
Total number of polymer chains6
Total formula weight126688.66
Authors
Castro, K.M.,Correia, B.E. (deposition date: 2024-05-07, release date: 2025-05-21)
Primary citationCastro, K.M.,Watson, J.L.,Wang, J.,Southern, J.,Ayardulabi, R.,Georgeon, S.,Rosset, S.,Baker, D.,Correia, B.E.
Accurate single domain scaffolding of three non-overlapping protein epitopes using deep learning
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.91 Å)
Structure validation

237735

數據於2025-06-18公開中

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