9F7Z

Crystal structure of human 4-1BB/TNFRSF9 in complex with the anti-4-1BB DARPin protein

Summary for 9F7Z

• Entry DOI: 10.2210/pdb9f7z/pdb
• Descriptor: anti-4-1BB DARPin, Tumor necrosis factor receptor superfamily member 9, beta-L-fucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: tumor necrosis factor receptor superfamily member 9; 4-1bb; tnfrsf9; darpin; designed ankyrin repeat protein; immune-oncology; molecular partners ag; proteros biostructures gmbh, protein binding
• Biological source: synthetic construct; More
• Total number of polymer chains: 16
• Total formula weight: 229136.70

Authors

Malvezzi, F.,Domke, C.,Hospodarsch, T.,Lammens, A.,Blaesse, M.,Krapp, S.,Reichen, C. (deposition date: 2024-05-06, release date: 2025-05-21)

• Primary citation: Saltarella, I.,Link, A.,Lamanuzzi, A.,Reichen, C.,Robinson, J.,Altamura, C.,Solimando, A.G.,Ria, R.,Vacca, A.,Frassanito, M.A.,Desaphy, J.F.; HUMAN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9 IN COMPLEX WITH LIGAND DARPIN HB01; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.81 Å)