9F78

BAZ2A bromodomain in complex with acetylpyrrole derivative compound 28-TN23

This is a non-PDB format compatible entry.

Summary for 9F78

• Entry DOI: 10.2210/pdb9f78/pdb
• Related: 9F6W 9F70 9F71 9F77
• Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, 1-[4-ethyl-5-[4-[(5-ethyl-1,2,4-oxadiazol-3-yl)methyl]piperazin-1-yl]carbonyl-2-methyl-1~{H}-pyrrol-3-yl]ethanone (3 entities in total)
• Functional Keywords: four helical bundle, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 25456.58

Authors

Dalle Vedove, A.,Cazzanelli, G.,Caflisch, A.,Lolli, G. (deposition date: 2024-05-03, release date: 2025-05-14)

• Primary citation: Dalle Vedove, A.,Cazzanelli, G.,D'Agostino, V.G.,Caflisch, A.,Lolli, G.; Unusual backfolded binding poses of BAZ2A bromodomain binders; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)