9F4V

UP1 in complex with EN300-118084

Summary for 9F4V

• Entry DOI: 10.2210/pdb9f4v/pdb
• Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide (3 entities in total)
• Functional Keywords: fragment screening, hnrnp a1, up1, rna/dna binding protein, up1-fragment complex, rna binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 22532.24

Authors

Dunnett, L.,Prischi, F. (deposition date: 2024-04-28, release date: 2024-05-08)

• Primary citation: Dunnett, L.,Prischi, F.; Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.4 Å)