9F44
cryo-EM structure of LST2 TOS peptide bound to human mTOR complex 1
Summary for 9F44
Entry DOI | 10.2210/pdb9f44/pdb |
EMDB information | 50183 |
Descriptor | Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8, Regulatory-associated protein of mTOR, ... (5 entities in total) |
Functional Keywords | mtor, mtorc1, lst2, zfyve28, egfr, tos, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 960506.97 |
Authors | |
Primary citation | Battaglioni, S.,Craigie, L.M.,Filippini, S.,Maier, T.,Hall, M.N. mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR Proc.Natl.Acad.Sci.USA, 2024 |
Experimental method |
Structure validation
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