9F40

Crystal structure of the NTD domain from S. cerevisia Niemann-Pick type C protein NCR1 with ergosterol bound

Summary for 9F40

• Entry DOI: 10.2210/pdb9f40/pdb
• Related: 9F41
• Descriptor: NPC intracellular sterol transporter 1-related protein 1, SULFATE ION, ZINC ION, ... (14 entities in total)
• Functional Keywords: ergosterol, vacuole, ncr1, membrane protein, niemann-pick type c protein
• Biological source: Saccharomyces cerevisiae (brewer's yeast)
• Total number of polymer chains: 4
• Total formula weight: 128159.98

Authors

Nel, L.,Olesen, E.,Frain, K.M.,Pedersen, B.P. (deposition date: 2024-04-26, release date: 2024-05-29, Last modification date: 2024-10-23)

• Primary citation: Jamecna, D.,Thaysen, K.,Nel, L.,Olesen, E.,Frain, K.M.,Szomek, M.,Langer, J.,Pedersen, B.P.,Wustner, D.,Hoglinger, D.; Structural and biochemical analysis of ligand binding in yeast Niemann-Pick type C 1-related protein; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.44 Å)