9EQJ
Crystal structure of pVHL:EloB:EloC in complex with MP-1-39
This is a non-PDB format compatible entry.
Summary for 9EQJ
Entry DOI | 10.2210/pdb9eqj/pdb |
Related | 9EQM |
Descriptor | Elongin-B, Elongin-C, von Hippel-Lindau disease tumor suppressor, ... (5 entities in total) |
Functional Keywords | e3 ligase, von hippel-lindau tumor-suppressor protein, ligase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 84310.56 |
Authors | |
Primary citation | Pierri, M.,Liu, X.,Kroupova, A.,Rutter, Z.,Hallatt, A.J.,Ciulli, A. Stereochemical inversion at a 1,4-cyclohexyl PROTAC linker fine-tunes conformation and binding affinity. Bioorg.Med.Chem.Lett., 110:129861-129861, 2024 Cited by PubMed: 38942127DOI: 10.1016/j.bmcl.2024.129861 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report