9EOG

PHF type tau filament from R406W mutant

Summary for 9EOG

• Entry DOI: 10.2210/pdb9eog/pdb
• Related: 9EO7
• EMDB information: 19854
• Descriptor: Microtubule-associated protein tau (1 entity in total)
• Functional Keywords: tf, tau filament, r406w, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 275519.23

Authors

Qi, C.,Scheres, S.H.W.,Michel, G. (deposition date: 2024-03-14, release date: 2024-05-29)

• Primary citation: Qi, C.,Lovestam, S.,Murzin, A.G.,Peak-Chew, S.,Franco, C.,Bogdani, M.,Latimer, C.,Murrell, J.R.,Cullinane, P.W.,Jaunmuktane, Z.,Bird, T.D.,Ghetti, B.,Scheres, S.H.W.,Goedert, M.; Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W.; Biorxiv, 2024; PubMed: 38746388; DOI: 10.1101/2024.04.29.591661

Experimental method

ELECTRON MICROSCOPY (3 Å)