9EJZ

Human M5 muscarinic acetylcholine receptor complex with mini-Gq, agonist acetylcholine and positive allosteric modulator VU6007678

This is a non-PDB format compatible entry.

Summary for 9EJZ

• Entry DOI: 10.2210/pdb9ejz/pdb
• EMDB information: 48110
• Descriptor: nanobody 35, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (9 entities in total)
• Functional Keywords: g protein-coupled receptor, acetylcholine binding, seven transmembrane protein, membrane protein
• Biological source: Lama glama; More
• Total number of polymer chains: 6
• Total formula weight: 158669.42

Authors

Burger, W.A.C.,Mobbs, J.I.,Thal, D.M. (deposition date: 2024-11-30, release date: 2025-08-13)

• Primary citation: Burger, W.A.C.,Mobbs, J.I.,Thal, D.M.; Structural insight into positive allosteric modulation of the M5 mAChR; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.06 Å)