9EFC

Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with TO-588

これはPDB形式変換不可エントリーです。

9EFC の概要

• エントリーDOI: 10.2210/pdb9efc/pdb
• 分子名称: Hdac6 protein, N-hydroxy-4-({(methanesulfonyl)[(pyridin-3-yl)methyl]amino}methyl)benzamide, ZINC ION, ... (5 entities in total)
• 機能のキーワード: potassium ion binding, alkali metal ion binding, ion binding, cation binding, metal ion binding, catalytic activity, hydrolase activity, deacetylase activity, protein deacetylase activity, acting on a protein, acting on carbon-nitrogen (but not peptide) bonds, in linear amides, tubulin deacetylase activity, zinc ion binding, transition metal ion binding, metal binding protein
• 由来する生物種: Danio rerio (zebrafish)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 80582.07

構造登録者

Erdogan, F.,Seo, H.-S.,Dhe-Paganon, S. (登録日: 2024-11-20, 公開日: 2024-12-04)

• 主引用文献: Olaoye, O.,Erdogan, F.,Gunning, P.T.; Bisected Cap Group Modifications Provides Basis for Improved Pharmacokinetics of HDAC Inhibitors; To Be Published,

実験手法

X-RAY DIFFRACTION (1.26 Å)